Tetanus is caused by a toxin released by a bacterial organism. The serum contains antibodies to the toxin produced by the bacterium Clostridium tetani. The antibodies inactivate the toxin in the blood stream and prevent an individual from experiencing tetanus.
prophylaxis and treatment of tetanus
Anti-tetanus serum drugs are the medications which are injected as a vaccine to prevent a person from getting tetanus. The most commonly used drug is called tetanus toxoid.
Anti-tetanus serum can be administered safely up to 48 hours post-injury, especially if the wound is considered high-risk for tetanus. However, the efficacy of the serum may decrease if there is a delay in administration. It’s crucial to assess the patient's tetanus vaccination history and the nature of the wound to determine the appropriate treatment. Consulting a healthcare professional for guidance is essential in such situations.
Even to day, some one comes and ask for ATS injection. Anti tetanus serum injection is very dangerous to give. The patient may get the anaphylactic reaction. This preparation is no longer used. Any serum preparation is dangerous. You need to be protected by anti tetanus injection. With proper wound care the anti tetanus serum is not required.
You give the antitetanus serum because it contains passive antibodies that can immediately start attacking any antigens if present. While that is going on, the body reacts to the toxoids injected into it by producing its own antibodies, this process is slow thus we need the antitetanus serum for immediate protection.
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anti tetanus serum
It binds to the tetanus toxin in your blood, blocking the toxin's action on the body's systems. If you have completed your tetanus vaccine schedule, anti-tetanus serum is not required as your blood already contains the apparatus to produce this itself.
Anti-tetanus serum is also known as tetanus immune globlulin. In the US, commercial brands available include HyperTet and BayTet. Blood from people who have been immunized with tetanus vaccine is processed to get the tetanus antibodies, which is injected to prevent tetanus in an un-immunized person.
Anti-tetanus serum is injected first to provide immediate passive immunity against tetanus toxins in case of a recent injury or exposure, as it contains pre-formed antibodies. Tetanus toxoid, on the other hand, is used to stimulate the body’s immune system to produce its own antibodies for long-term protection. Administering the serum first ensures that the patient has immediate protection while the active immune response from the toxoid develops over time. This combination approach maximizes both immediate and sustained immunity.
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ATS means Anti Tetanus Serum.