The elimination half-life of codeine typically ranges from 2.5 to 4 hours, although it can vary depending on individual factors such as metabolism, age, and overall health. Generally, it takes about 5 to 6 half-lives for a drug to be mostly eliminated from the body, so codeine can be expected to remain in the system for approximately 12 to 24 hours after the last dose. However, metabolites like morphine, which is produced when codeine is metabolized, may be detectable for a longer period.
No, codeine and codeine phosphate are not the same. Codeine is an opiate used as a painkiller and cough suppressant, while codeine phosphate is a salt form of codeine that is commonly used in medications for pain relief and cough suppression. The addition of phosphate to codeine can affect its solubility and how it is metabolized in the body.
Codeine is a depressant opiate. It depresses the Central Nervous System (CNS). Codeine is a pro-drug. It converts to morphine in the body.
elimination
The large intestine prepares wastes for elimination from the body
In biological terms, elimination is the process by which an organism ejects some unwanted substance from its body.
The only antidote for codeine is time, unless it was an overdose. Then the antidote is the emergency room.
Defecation or elimination is the process of removing undigested food (feces) from the body.
Roughly 72 hours.
The large intestine prepares wastes for elimination from the body.
The elimination rate constant in pharmacokinetics is calculated by dividing the natural logarithm of the drug concentration at two different time points by the time difference between those points. This helps determine how quickly a drug is removed from the body.
The elimination
Excretion.Excretion