Barbiturates -- now nearly never prescribed -- are hypnotics, used predominantly as sleeping pills as late as the 1970s. They depress respiration and have a surprisingly low lethal dosage (which is why they're almost never given as a prescription anymore). Also, they have a deadly synergistic effect when combined with ethanol (booze) that makes them even more deadly.
They're highly addictive, not just in the habituating sense, but physiologically so. Stopping a barbiturate addiction cold turkey (all at once without help and without tapering off) may in and of itself be lethal, often causing convulsions. Detoxing barbiturates is an inpatient procedure and not a small one.
Development of tolerance is extremely rapid too.
Once a popular sleeping prescription and a huge black-market item, barbiturates are nearly gone, both from the legal and black-market drug scene.
the greast risk of long term affects is phycal dependance
Your greatest danger is Panic
The greatest danger is flying or falling debris
The greatest danger from getting HPV is cancer and death.
The answer is a loaded gun
stampedes
Packing Group I (PG I) is the greatest danger; Packing Group III (PG III) is the least.
The greatest danger in Antarctica is freezing to death by hypothermia.
The greatest danger for a person with hypothermia, unless treated in time, is death.
Hunters.
Barbiturates are usually swallowed but sometimes barbiturates are injected and this can be extremely dangerous. =)
I should think above anything we are the greatest danger. for example wild tortoises are taken from the wild and illegal transported and sold as pets
Infections.