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Q: What is the osmotic gradient in the medullary interstitium of the kidneys?
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The mechanism that establishes the medullary osmotic gradient depends most on the permeability properties of the?

loop of Henle


Is osmotic a diuretic?

Osmotic diuretics are a type of diuretic not a specific drug. Osmotic diuretics work by increasing blood flow to the kidneys and preventing the tubes in the kidneys from making such concentrated urine so that there is no gradient for water to be reabsorbed so you will pee all that water out. An example of an osmotic diuretic is mannitol.


Difference between osmotic diuresis and water diuresis?

Osmotic Diuresis Water diuresis *High amount of H2O reabsoebed in *Normal absorption. PCT. *A lot of solutes are lost. *loss of solute amount is less. *Very high amounts of urine are *Amounts of urine produced are less produced. than that in osmotic diuresis. *Low medullary osmolality. *High medullary osmolality. *Normal *The limiting concentration gradient *The limiting gradient is not reached. for Na is reached at PCT. *Hyponatremia may occur. *Takes more time to get hyponatremia.


What is the main factor that creates the high osmotic gradient between the cortex and medulla?

A high osmotic gradient between the cortex and the medulla is caused by the running, walking, or jumping of a human person. These simple actions cause the osmotic gradient to rise significantly.


The osmotic gradient ____ as it moves deeper into the medulla?

Increases


Where is osmolarity greatest in kidney?

Osmolarity is greatest in the innermost portion of the medulla near the renal pelvis due to the osmotic gradient. As one goes deeper into the renal medulla, the osmotic gradient increase. The osmolarity varies from 300 mOsm at the edge of the medulla to the innermost at approximately 1200-1400 mOsm. Think of the movie, Silence of the Lamb, when Anthony Hopkins eats that kidney, as he eat closer and closer to the kidney, it get salter. The medullary osmotic gradient is used for water reabsorption in the collecting duct, when ADH is present, thus increasing blood volume and result in increasing blood pressure.


How is urea reabsorbed?

40-50 % of filtered urea is reabsorbed through passive diffusion in the Proximal Convoluted Tubules. Loop of Henle, Distal Convoluted Tubules and Cortical Collecting Ducts are impermeable to urea. But secretion of urea happens in descending Loop of Henle (This helps to maintain the osmotic gradient in the medulla of the Kidney). There is also re-absorption of urea in the medullary collecting ducts.


Why is it easier to move materials across membranes down a concentration gradient?

osmotic pressure


Why do kidneys require so much energy to function?

They're doing a lot of work. About 1/5 th of your blood is filtered every minute - a good bit of what is filtered out must be reabsorbed (against an osmotic gradient) and that all takes energy.


Which term describes describes the difference in the concentration of a substance across a cells membrane?

This is called the osmotic gradient.


True or false Obligatory water reabsorption involves the movement of water along an osmotic gradient?

false


Which term describes the difference in the concentration of a substance across a cells membrane?

concentration gradient