ATP synthase is a key enzyme in energy transformation of a living cell. The enzyme makes adenosine triphosphate (ATP) from adenosine diiphosphate (ADP) and inorganic phosphate (Pi).
ADP + Pi <=> ATP ATP is a universal "energy currency" of a living cell and is essential for DNA synthesis, muscle contraction, ion and nutrients transport, signal transduction, etc.
The amazing feature of ATP synthase is rotary catalysis: a complex of subunits rotates relative to the rest of the enzyme and the mechanical energy of rotation is driving ATP synthesis reaction.
In turn, the rotation is powered by transport of protons trough the membrane segment of ATP synthase. The driving force for this transport is the electrochemical potential difference of proton across the membrane.
ATP synthase is therefore the smallest mechano-electro-chemical energy transducer that works as a nanoturbine.
A much more detailed description of ATP synthase is available at
www.atpsynthase.info
Yes, ATP synthase is an enzyme that plays a key role in the production of ATP in cells.
Yes, ATP synthase is a protein.
Yes, ATP synthase is an integral protein.
Synthase enzymes are involved in the synthesis of ATP during photosynthesis. They play a crucial role in the conversion of light energy into chemical energy, which is essential for the plant to carry out various metabolic processes.
In the presence of a metabolic poison that inhibits mitochondrial ATP synthase, the pH difference across the mitochondrial membrane would increase. This is because ATP synthase plays a crucial role in generating ATP by utilizing the proton gradient (pH difference) across the membrane. Inhibition of ATP synthase would disrupt ATP production, leading to a buildup of protons on one side of the membrane.
Yes, ATP synthase is an enzyme that plays a key role in the production of ATP in cells.
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ATP synthase is not directly involved in the Krebs cycle. However, it plays a crucial role in oxidative phosphorylation, which occurs after the Krebs cycle in cellular respiration. ATP synthase generates ATP by utilizing the energy released during the flow of protons through the inner mitochondrial membrane.
Yes, ATP synthase is a protein.
ATP synthase catalyzes the addition of a phosphate group to an ADP molecule. ADP + ATP synthase + P --> ATP + ATP synthase (ATP synthase on both sides of the equation indicates that, as an enzyme, it is not used up in the reaction.)
Yes, ATP synthase is an integral protein.
Synthase enzymes are involved in the synthesis of ATP during photosynthesis. They play a crucial role in the conversion of light energy into chemical energy, which is essential for the plant to carry out various metabolic processes.
In the presence of a metabolic poison that inhibits mitochondrial ATP synthase, the pH difference across the mitochondrial membrane would increase. This is because ATP synthase plays a crucial role in generating ATP by utilizing the proton gradient (pH difference) across the membrane. Inhibition of ATP synthase would disrupt ATP production, leading to a buildup of protons on one side of the membrane.
The catalytic knobs of ATP synthase would be located on the stromal side of the membrane. Protons travel through ATP synthase from the thylakoid space to the stroma.
ATP Synthase
At least 10 protons pass through ATP synthase in order to make a molecule of ATP.
ATP synthase is a protein that synthesizes adenosine diphosphate (ADP) and an extra phosphate together into adenosine triphosphate (ATP). ATP is a very crucial molecule in body chemistry, and its primary function is to serve as an energy source for the vast majority of cellular functions. Therefore, the role of ATP synthase is to provide the energy that keeps cells functioning.