if you dont wanna waste your master ball, then the strongest ball will be the Ultra Ball...
Lugia its easier.
Mewtwo I guess????
Master Ball
NO WAY! sorry for those of you that it is too late for, but you should save your master ball for Mew or Mewtwo!
well, lengrndarys like the birds and mewtwo are hard to catch. but then theres the lengendary dog. personally i used my master ball on moltres and it took only 2 ultras for mewtwo
mew two and feraligator are the best chance
by defeating Giovanni, the rocket leader, in the Silph Co. building. After ask the president and he will give you a master ball(you should save it for Rikou, Entei, Suicune, or Mewtwo)
master ball if you havent already used it.
Feraligator, Snorlax, Mewtwo, Eevee or an evolved form(preferably Jolteon), Lugia, and Teddiursa. All should be at least 70.
If you don't want to waste time using other balls, yes, u should. But it is possible to nab him with another ball. Lueroi, a good Youtube video maker, caught Mewtwo with a GREAT BAll. He used his master ball on something else. If you don't want to waste your MAster ball, don't.
master ball, paralyze and block, false swipe and random balls
in firered, mewtwo in platinum, diamond, and pearl, mesprit those are just suggestions. pick the one you like most