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The nervous system and the circulatory system are needed for the endocrine system to work properly. The pituitary gland and the hypothalamus are located in the brain and are part of the endocrine system. The cardiovascular system is needed to transport the various hormones through the body. Hormones are a chemical form of remote control, and it is the blood that carries the hormones made by the endocrine system to all the tissues that respond to them.

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