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I would suggest keeping a close eye on your dog and let him ride it out. There are no specific reversal agents for diphenhydramine (the active ingredient in Benadryl), so a veterinarian will simply be watching your dog for signs of problems and you can do that at home.

Benadryl overdose can result in issues like stupor and neurologic deficits. If you see seizure-like activity, or your dog's breathing rate or heart rate drop too low (normal breathing rate should be about 20/minute, normal heart rate about 80/minute), you need to get your dog to a veterinarian.

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11y ago

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