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Troponin is a major component of muscle tissue. It is composed of troponin C, troponin I, and troponin T. Troponin interacts with tropomyosin and myosin to create muscle contraction.
It is involved in the regulation of the contraction of a cross-striated muscle.
The three parts to troponin are troponin C, which binds calcium ions, troponin I, which inhibits the interaction between actin and myosin, and troponin T, which anchors troponin complex to tropomyosin.
The theraputic troponin level is 0.00.
Troponin testing is done to diagnose heart attacks (myocardial infarctions).
cardiac troponin I tests measure only cardiac troponin; tests for cardiac troponin T may cross-react with troponin found in other muscles and give positive or increased results in the absence of heart damage.
Troponin is a cardiac enzyme that your heart releases under stress.
Actin and myosin
Both troponin T and I are cardiac markers used to diagnose myocardial infarctions.
Emily Jane Austin has written: 'Characterisation of the interaction sites between Troponin T and Troponin C of the Troponin complex from human cardiac muscle'
At rest, tropomyosin is held in place by troponin, which is a regulatory protein located on the actin filaments of muscle cells. Troponin binds to both tropomyosin and calcium ions, stabilizing the position of tropomyosin and preventing actin-myosin interaction.
The sample bottle typically used for troponin testing is a lithium heparin tube or a serum separator tube. These tubes help preserve the stability of troponin levels for accurate testing.