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The invention of the cotton gin. With the ability to pull the seeds from the cotton bolls without picking them out by hand the plantation owners were able to grow more cotton and needed more slaves.

This was mainly because of natural reproduction - American Pageant 13th Edition

They called slave women with 10 or more children "rattlin good breeders"

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Q: What was The great increase of the slave population in the first half of the nineteenth century was largely due to?
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