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Neurotransmitters would continue to bind and rebind with the postsynaptic receptors, which would continue induction of a signal in the postsynaptic neurons, which would repropagate the initial signal.

The case in drugs that block reuptake transporters (such as in serotonin reuptake inhibitor and norepinephrine reuptake inhibitor antidepressants, and dopamine reuptake inhibition found with cocaine and methylphenidate).

This is also seen in cases where drugs block the breakdown of neurotransmitters at the synapse:

- monoamine oxidase inhibitors (MAOIs) - Nardil, Parnate, selegiline - which prevent the breakdown of serotonin, norepinephrine, and dopamine

- acetylcholinesterase inhibitors (AChE inhibitors) - organophosphase pesticides, nerve gas, racetams

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13y ago

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