the molecule that binds is costraynim it is a very rare molecule and is very hard to find you can find it in volcanoes and in the sea the one that is found in the sea is much different than the one in the volcanoes but they both bind to calcium during muscle contraction the one in the sea has a circulating point which can be changed if it is riied with different nature such as land the one in the volcano is very hard to take out but it is possible it has to be cooled with nitrogen straight away for more than twenty four hours before any human being can touch it with their bare hands
in skeletal muscle calcium ions binds to troponin
It binds to Troponin which then frees the myocin bonding sites on the Actin.
troponin
Troponin
troponin
Calcium is released from the sarcoplasm to bind with the troponin which allows the tropomyosin the reveal the binding sites on the actin so the muscle can contract
Once a triad has been achieved, Calcium ions get released. Once they're released they bind to troponin, which helps begin muscle contraction.
Calcium ions bind to troponin, changing troponin's shape
Calcium binds to the messenger protein Calmodulin. The calcium-calmodulin complex then activates myosin light chain kinase (MLCK), which phosphorylates myosin to allow it to bind to actin - producing contraction.
They bind to regulatory sites on troponin to remove contraction inhibition
tendons - bind muscle to muscle ligaments- bind muscle to bone
Sarcolema receptors
Calcium binds to troponin, which moves the tropomyosin out of the way so that myosin can bind to actin; this ultimately causes a power-stroke.
Calcium bridges form between muscle cells. The calcium ions bind to troponin-tropomyosin molecules in the grooves of actin filaments and form crossbridges.
Calcium ions bind to the thin filament ( actin ), turn it and expose the binding site to the thick filament (myosin ).
It blocks the nicotinic cholinergic receptors on the muscle that normally bind the acetylcholine released by the motor neuron.
They are needed for contraction and also for relaxation: - For contraction: actin has active sites for binding to myosin, and myosin heads have ATPase activity (ATP hydrolization provokes a conformational change in the myosin head that pushes the actin filament and that is called the "power stroke), and at the end the sarcomere (sorry, google it) shortens. This repeats until calcium levels get lower again (because calcium allows actin to bind myosin, because there are other proteins - troponin, tropomyosin - that block this binding when calcium is not present). This is the cross-bridges cycle. - For relaxation: we have said that calcium ions are necessary for contraction, but we don't want our muscles to contract forever. That's why we need a mechanism to reduce intracellular calcium concentration. That mechanism is a calcium pump (called SERCA) that puts calcium ions again inside the "sarcoplasmic reticulum", which is a kind of storage compartment for calcium in skeletal muscle. This sarcoplasmic reticulum is very developed in skeletal muscle (in contrast with smooth muscle). SERCA pumping is also ATP dependent (active transport). As a curiosity, inside of the sarcoplasmic reticulum, calcium ions (Ca2+) bind to another protein called calcequesterin. They are needed also for processes intrinsic of excitable cells (aka neurons and muscle cells), such as the sodium-potassium pump (active transport)