Hemophilia are divided into severe, moderate and mild diseases depending on the level of functional factor VIII or factor IX. (normal levels are between 50% and 150%)
Mild hemophilia patients (factor levels>5% and <50%) bleed only after injury, invasive procedure or surgery. Carriers of hemophilia are also sometimes found to have factor levels in the Mild range.
Moderate hemophiliacs (factor levels - 2to 5%) experience more bleeds, about once a month, usually after trauma, surgery or extreme exertion. They usually bleed in the muscles and joints. Once a bleeding occurs in a particular area, these patients may continue to have bleeding episodes in those areas.
Severe hemophiliacs (factor level<1%) bleed spontaneously usually in joints, muscles and soft tissues.
Joint and muscle bleeding may cause pain, tingling, heat, swelling, limited range of motion etc. It commonly occurs in the ankles, elbows and knees but can also affect any joint in the body.
Rarely, bleeding can occur in mucous membranes such as the mouth, tongue, throat, nose etc. Hematuria may also occur. Central nervous system bleeds such as intracranial or spinal cord bleeds are life threatening and may present as stiff neck or back , headache, vomiting, confusion, change in behavior, slurred speech, focal deficits or unequal pupils. Other sites where major bleeds may occur is neck, throat, eye, GI system, hip, testes, retroperitoneum and following severe injury.
Hemophilia A is inherited as a recessive trait.
There are two types of hemophilia: hemophilia A (sometimes called classical hemophilia) and hemophilia B (sometimes called Christmas disease). Both are caused by a low level or absence of one of the proteins in the blood (called factors) that control bleeding. Hemophilia A is caused by a deficiency of factor VIII, and hemophilia B is caused by a deficiency of factor IX. There is no difference between the two types of hemophilia, except that hemophilia B is about five times less common than hemophilia A.
Yes, it is possible to develop hemophilia later in life, although it is rare. Acquired hemophilia can occur in adults due to certain medical conditions or medications that interfere with the body's ability to clot blood.
Hemophilia is a hereditary bleeding disorder where a person lacks certain clotting factors, such as Factor VIII or Factor IX. This can result in prolonged bleeding and difficulty forming blood clots, leading to potential serious complications if not managed properly. Treatment often involves replacing the missing clotting factors through infusions.
It is very much recessive with only one exception, which is that there is a large portion of women who simply carry the trait but dont actually have it. If you are to procreate with a female carrier than your chances of having a hemophiliac child are still not very high. You can find all the info you need by using a Punnett Square method to figure out the chances of hemophiliac children with 2 parents.
yes hemophilia can be detected before birth
Hemophilia is one disease in which blood does not clot normally. von Willebrand's Disease
There is no chance that the child will have hemophilia even if the spouse has hemophilia. Any girls the couple has will be carriers if the spouse has hemophilia.
50%
Can anyone be a candidate for the hemophilia a
Hemophilia is caused by a deficiency of clotting factor VIII (hemophilia A) or clotting factor IX (hemophilia B).
50%
There are no hard answers to this, it depends strictly on luck. The statistics are though not very good for their children. Statisically the couple have a chance of having a normal son, a daughter that is a carrier for hemophilia, a daughter with hemophilia and a son with hemophia.
50 million ppl have hemophilia
No, Hemophilia is a genetic disease. A person is born with it.
The classical spelling of hemophilia is haemophilia.
Hemophilia is when your blood clots slowly or not at all.