Mexico City.
Mexico City, Mexico.
In Mexico City, Mexico.
The major North American city closest to the coordinates 45 N 76 W is Ottawa, the capital city of Canada. Ottawa lies very close to these coordinates, making it the city that is most proximate to this location in the North American region.
I can't find any labeled North American city, town, or village at that latitude. The nearest one is Jagüey Grande in central Cuba, at 22.525° North.
Nope
Omaha
Anchorage
Mexico City is the most populous city in North America. It has a population of 8.851 million people as of 2014.
Toronto City Saints was created in 2010.
Florida
Mexico City.