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Autologous = own marrow

Allogeneic = transplant from a related (or tissue matched) donor.

Syngeneic = transplant from an identical twin.

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13y ago
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10y ago

A bone marrow transplant from the patient's own cells is called an autologous transplant.

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14y ago

autologous bone marrow transplant

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Q: When the donor is the patient himself it is what type of bone marrow transplant?
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What is allogeneic bone marrow transplantation?

In a procedure called "allogeneic bone marrow transplant," a donor is found whose marrow matches that of the patient.


What kind of bone marrow transplantuses bone marrow from a doner?

All bone marrow transplants require bone marrow from a donor; the purpose of the transplant is to replace the patient's bone marrow (that no longer works) with some that does work, which clearly cannot come from the patient (since they have none that works). Hence a donor must be used.


What type of bone marrow transplant usues bone marrow from a donor?

allogenic


What is Marrow replacement process?

This is bone marrow transplant. A compatible donor should be screen and crossmatch before they can perform the transplant.


What is the bone marrow transplant uses healthy bone marrow cells from a compatible donor such as a sibling?

Sometimes. In an allogeneic bone marrow transplant the bone marrow is taken from a donor and infused into a recipient. Usually the recipient has undergone intensive radiation therapy in order to wipe out the immune system so that it will not attack the foreign bone marrow cells (reject it) and the donor marrow has had some cells that would attack the recipient removed. In an autologous transplant bone marrow is removed from the patients, treated in some way, and then infused back into the patient. It can be frozen and saved while the patient undergoes some kind of therapy and then thawed and reinfused. In a syngeneic transplant marrow from one identical twin is infused into the other twin. This one is pretty cool because no treatment is needed to prevent rejection (but the recipient will probably still receive treatment for the disease.


Some Facts About Bone Marrow Transplant?

A bone marrow transplant is the transplant of marrow cells and blood from a healthy person to a person who is in need of marrow and blood cells. The healthy blood and marrow replace the diseased cells of the sick person. The marrow cells are stem cells, which means they can develop into red blood cells, white blood cells and platelets.Who Needs a Bone Marrow Transplant?People who have blood cancers like leukemia may need bone marrow transplants. Leukemia is a malignant overgrowth of white blood cells in the bone marrow, the lymph glands, the spleen, the liver or other organs that are part of the lymphatic system. Other candidates for the transplant are:People whose suffer from thalassemias, where the red blood cells contain less hemoglobin than normal.People who suffer from aplastic anemia, where the bone marrow doesn't produce enough blood cells.People who suffer from sickle cell anemia, where the red blood cells are deformed and can't carry hemoglobin properly. Sickle cell anemia causes episodes of extreme pain and chronic poor health and can be life threatening.Sometimes radiation and chemotherapy can damage bone marrow to the point where it can't produce blood cells, so a bone marrow transplant is needed.Who Gives a Bone Marrow Transplant?The patient can give a bone marrow transplant to themselves. If the patient was healthy and had to have treatment where the destruction of their bone marrow was a possibility, they can have their bone marrow stem cells stored.Other bone marrow transplants come from a donor. The problem here is that the donor's stem cells have to match the patient's very closely. Sometimes, even a brother, sister or parent isn't a match for the patient and there might be a wait till a donor is found.Sometimes the donor cells come from umbilical cord blood.How Is Bone Marrow Collected?Nowadays, doctors rarely perform the painful procedure where marrow is taken out of the donor's hip, but in most cases a needle withdraws blood from the donor's arm. The stem cells are removed from the blood and what's left of the donor's blood is returned to them.


How many types are there of bone marrow?

There are three types of bone marrow transplant procedure. One of the three is called an Autologous bone marrow transplant. With an Autologous bone marrow procedure, doctors take the persons own bone marrow and freeze it before chemo then reintroduce the marrow into red blood cells after chemo or radiation. The second type is Allogeneic. In an Allogeneic marrow procedure the marrow is taken from a matching marrow donor. The third type is called Umbilical cord blood transplant. With an umbilical cord blood transplant, there can be a wider variety of donor as the cells are still considered immature.


What type of bone transplant uses bone marrow from a donor?

Either a bone marrow or a stem cell transplant (although these days most stem cell transplants are obtained from blood).


What are the successful results of a bone marrow transplant?

In a successful bone marrow transplant, the donor's marrow migrates to the cavities in the recipient's bones and produces normal numbers of healthy blood cells. Bone marrow transplants can extend a person's life, improve quality of life.


Can a bone marrow transplant change the DNA of the new blood cells?

Sort of... Assuming there is no GVHD and the bone marrow transplant is successful, a blood test will show what percent of the recipient's blood is their own blood and what percent of the recipient's blood was produced from the donor's bone marrow. If the test comes back ">95%", then the recipient's blood and the donor's blood have become DNA-identical. Interestingly enough, the recipient's hair and saliva remain the same DNA they were born with. Their hair and saliva do NOT change to the donor's DNA. So, the recipient of the bone marrow transplant would then have two DNA's in their body. Neat stuff!


What is the life expectancy of a patient with stage 3 kidiney disease?

what is the life expectancy of a kidney transplant patient with a living donor


Can you be a bone marrow donor if you are taking methadone?

It is highly unlikely the transplant team will risk the donation. Both the recipient and the donor could be at risk. Methadone does affect bone marrow both by its use and because of why it is being used. High risk behavior including using injectable drugs and unsafe sexual practices while high leaves the possible donor suspect for HIV and other diseases. While offering bone marrow is a noble gesture, the risk to the patient is high.