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Lortab "10" is generally referred to Hydrocodone 10mg's/Acetaminophen 500mg's.

Norco "10" is generally referred to as Hydrocodone 10mg's/Acetaminophen 325mg's.

Hydrocodone is the analgesic, or (aka) the main active pain reliever in both medications. Which is opiate based.

The Acetaminophen is Tylenol. A slight analgesic itself but is only a slight help for pain that requires Hydrocodone or above mixed.

The Apap is synergistic with the Hydrocodone in that it slightly thins the blood allowing for arguably better absorption combined with its own pain killing properties.

Some argue the Tylenol is added so abusers will annihilate their livers by over use. Which happens often,.. even with just Tylenol. As Tylenol is very Hepatoxic. But that is another argument/question.

So, with the Lortab you swallow 500mg's per pill/tablet - with the Norco 325mg's per pill tablet. (Of Tylenol) --- Per 10mg's of Hydrocodone ingested.

To err on the side of safety I would go with the lowest Tylenol content available.

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14y ago

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