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Nerve agents are chemical warfare agents that have the same mechanism of action as OP organophosphate pesticides or insecticides. They are potent inhibitors of acetylcholinesterase . Cholinergic syndrome consisting of copious respiratory and oral secretions, diarrhea and vomiting, sweating, altered mental status, autonomic instability, and generalized weakness that can progress to paralysis and respiratory arrest.


The amount and route of exposure to the nerve agent or OP pesticide, the type of nerve agent or pesticide will contribute to the time of onset and the severity of illness. For example, inhalation of a nerve agent or an OP pesticide leads to a quicker onset of poisoning with more severe symptoms when compared to with dermal exposures, given the same amount of agent.


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