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Colonel Sam Daniels is a fictional character portrayed by actor Dustin Hoffman in the 1995 film "Outbreak," directed by Wolfgang Petersen. He is an Army virologist who leads a team to combat a deadly virus outbreak in a small California town. The character is depicted as resourceful and determined, navigating military and scientific challenges to contain the threat and save lives. The film explores themes of epidemic response and the ethical dilemmas faced by those in power.

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