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RBC's die because they eject their nucleus during their formation in order to make more room for hemoglobin. Without a nucleus they are unable to make repairs and due to the stresses of traveling within the cardiovascular system. As a result they last on average about 120 days.

Worn out RBC's are removed from circulation in the spleen and liver. The heme and globin portions of hemoglobin are split apart. The globin is broken down into amino acids which can be used to synthesize other proteins. Iron is removed from the heme portion and used to synthesize new heme molecules. The non-heme portion goes through a series of chemical transformations and eventually ends up as something called sterocobilin which is what gives feces it's characteristic brown color.

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The primary source of RBCs in the adult human being is the bone marrow in the shafts of the long bones?

That's correct. Red blood cells (RBCs) are primarily produced in the bone marrow of long bones like the femur and the humerus in adult human beings. The bone marrow contains stem cells that differentiate into specialized blood cells, including RBCs.


What is the compatibility testing for agglutination of donor RBCs by the recipeints' serum?

Compatibility testing involves mixing donor red blood cells (RBCs) with recipient serum to check for agglutination. If agglutination occurs, it indicates incompatibility between the donor RBCs and recipient serum, suggesting a mismatch that could lead to a transfusion reaction. Testing is crucial to ensure safe blood transfusions.


What is the significance of RBC enumeration?

RBC (red blood cell) enumeration is important for diagnosing conditions like anemia, polycythemia, or other blood disorders. It can also provide information about oxygen-carrying capacity and overall health status. Monitoring RBC levels helps in assessing response to treatments and identifying any potential health risks.


How do you compare RBC from WBC?

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