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Why are only monosubstitution products obtained in the acylation of the substrate compounds chosen in friedel crafts acylation?
Wiki User
∙ 10y ago
because the group added is a withdrawing group that deactivates the ring
Wiki User
∙ 10y ago
Only monosubstitution products are obtained in the Friedel-Crafts acylation reaction because once an acyl group is attached to the substrate compound, it becomes a deactivating group, making further substitutions less favorable. This prevents the formation of disubstituted or polysubstituted products.
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