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This is a combination of Sulfamethoxazole with Trimethoprim used to treat bacterial infections.About 10 % patients areallergicto it. (Sulfa drug.) So with so many better alternative antimicrobial drugs in hand, doctors avoid using this combination. Apart from drug induced rash, 'which mayaggravatein sun light', patient can have many reactions, though rare, like Agranulocytosis, Steven Johnson syndrome,Erythemamultiform e, Exfoliative dermatitis. So better avoid this drug above 5 years and below six months of age.

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