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Large animals require a circulatory system so that they are able to efficiently distribute materials throughout their body. The circulatory system consists of the heart, blood vessels, blood, lymph, lymph vessels, and associated organs such as the thymus, spleen, and liver. Various functions include: transport of nutrients from the digestive system and storage depots to each cell, transport of oxygen from respiratory structures, transport of metabolic wastes from cells to excretory organs, transport of hormones, helps to maintain fluid balance, distribute metabolic heat, maintain the approprate pH and help defend against invading microorganisms.

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