Why does the incidence of Down syndrome increase with maternal age?
As a woman gets older, her eggs start to break down and wear out. This is the reason that she is more likely to have a child with Down Syndrome as she ages.
For instance, the chance of having a baby with Down syndrome is one in 378 for a 35-year-old woman and increases to one in 30 for a 45-year-old woman
1 out of every 733 births.
Varying statistics reported by our users: 2 percent of the world's population has Down syndrome. According to Wikipedia, 0.1-0.125 % of babies who are born have Down syndrome (1 in every 800-1000 births). The overall incidence of Down syndrome is 1:660 newborns, thereby making it the most common genetically diverse configuration in humans. Research shows that 1:800-1000 people (approximately 900) are born with Down syndrome. If you compare this with the number of people on… Read More
The rate of incidence of males and females with Down syndrome is the same. Both sexes are affected equally.
Where can you find information about someone who has both Down syndrome as well as Klinefelter's syndrome?
Causes of Klinefelter Syndrome The additional sex chromosomes in men with Klinefelter syndrome results from nondisjunction during meiosis and may have a paternal (50 to 60 percent) or maternal (40 to 50 percent) origin. This contrasts with Down syndrome, which is caused predominantly by maternal nondisjunction and inheritance of the extra chromosome 21 from the mother.
There are studies (Am J Epidemiol 1997; 145: 134-47) indicating that Hispanics possibly have a higher incidence at maternal age under 40. The question is as always, how reliable are those numbers.
According to the U.S. National Institutes of Health, the overall rate of incidence of Down Syndrome is 0.13% (1 in 750); but this figure is misleading since the incidence is highly related to the age of the mother. For mothers below age 30, the incidence of Down Syndrome is 0.10% (1 in 1000); but it increases dramatically after age 30. At age 41, the risk of giving birth to a Down Syndrome child is 10… Read More
It is a chromosomal abnormality due to increased maternal age, it does not spread.
Down's syndrome is increased with advanced maternal age, which is defined as more than 35 years of age.
Maternal age influences the odds of conceiving a baby with Down syndrome. The incidence of Down syndrome in a woman under 30 is approximately 1:1,000, according to the National Institutes for Health (NIH). This increases to approximately 1:400 by the age of 35, and to 1:12 by age 49. Some breakdown figures from our contributors At the maternal age of 20-24, the probability is 1:1562 At 37, the odds of having a child with Down… Read More
The incidence, however, increases dramatically with increasing maternal age. If you look at the link below, under about age 30, there is a 1:1000 chance in having a child with Down syndrome, however, at age 40, there is about a 1:100 chance. This increases to 1:10 by age 50. 80% of all children with Down syndrome are born to women under the age of 30, however, because women of this age group have children at… Read More
* Down syndrome, caused by trisomy of the 21st chromosome, overall is seen in about 1 in 750 live births. The incidence, however, increases dramatically with increasing maternal age. If you look at the link below, under about age 30, there is a 1:1000 chance in having a child with Down syndrome, however, at age 40, there is about a 1:100 chance. This increases to 1:10 by age 50. 80% of all children with Down… Read More
If a woman had a distant relative or an ancestor with Down syndrome would it increase the chances that this woman would bear a child with Down syndrome?
I would say no. Down Syndrome is caused by an extra chromosome (extra pair of chromosome 21). If anyone has three chromosomes 21, they have Down; you can't have "latent Down" and transmit it to your children. What increases the risk for Down most is older parental age, especially maternal (>35, and especially >40). Most standard prenatal screenings now can detect Down in the fetus very early on.
The association of Hirschberg with Downs is well-recognized with an incidence of 7.32%
Down Syndrome is spread fairly evenly between males and females. There does seem to be a slightly higher incidence among males, however.
Though actual figures are not available for all countries the average incidence of Downs syndrome is approximately 1 in 800 live births.
The only maternal characteristic to show a strong enough association to imply any causation is advanced maternal age, some sources reporting >35 years and some up to >45 years.
If you have a brother or a sister with Down syndrome does this increase the chances of giving birth to a child with Down syndrome?
no if the one of the parents have it and it is genetic then yes. but in this case no because it is not genetic
Yes. Having children over the age of 35 can increase the chance of Down Syndrome.
The reason that older age of the mother will increase the risk of Down syndrome in babies is because older eggs have more of a chance of chromosomes not dividing properly.
After having one child with Down syndrome what is the likelihood of having another child with Down syndrome?
After having one child with Down Syndrome, the likelihood of having another is about one percent. If the first child's Down Syndrome is due to translocation trisomy 21, the likelihood of another Down Syndrome child increases. As far as researchers know at this point, Down Syndrome is not attributed to the parents' behavior prior and/or during pregnancy or any environmental factors. The incidence of Down Syndrome does rise if the mother is older than 35… Read More
Umm, no. You're either born with or without Down syndrome. It's not a disease, it's a genetic condition.
This with Down syndrome can indeed have children without it. However, the chance of having a child with Downs is increase because of the parent being a carrier.
Theres really only one important risk factor; Age and maternal age only. The risk for having a child with Down syndrome increases signifficantly after the mother reaches 35-40 years of age.
approximately half of the offspring of someone with Down syndrome also have the syndrome themselves
The Occurrence of Down Syndrome Most of the time, the occurrence of Down syndrome is due to a random event that occurred during formation of the reproductive cells, the ovum or sperm. As far as we know, Down syndrome is not attributable to any behavioral activity of the parents or environmental factors. The probability that another child with Down syndrome will be born in a subsequent pregnancy is about 1 percent, regardless of maternal age… Read More
Down syndrome is a genetic abnormality and would be called a genetic disorder; however, complications associated with Down syndrome can increase the risk of a number of diseases, such as congenital heart disease. To give another example, cancer is a disease, but in some it may stem from a genetic disorder.
What is the most common chromosomal abnormality seen in live born babies what is the prevalence of this disorder what is the relationship between maternal age and the risk of having a baby with this?
Down Syndrome-the rest is on wikipedia
Down Syndrome and Turner Syndrome are two completely different places. Even though this is not how i found out, the clue is in Down Syndrome and Turner Syndrome.
No, you cannot. Down syndrome is a syndrome that is with you from birth.
Most cases of down syndrome are not inherited. Translocation Down syndrome can be inherited.
That depends. Men with Down syndrome have been shown to be sterile, while women with Down syndrome are capable of carrying a child, with 50% likelihood that the child will be born with Down syndrome.
At age 30, for example, a woman has about a 1 in 900 chance of conceiving a child with Down Syndrome. Those odds increase to about 1 in 350 by age 35. By 40 the risk rises to about 1 in 100. It occurs by going through fermentation and supplies alcohol in the brain resulting in down syndrome.
Down syndrome IS the diagnosis.
Down Syndrome Is In Your Brain.
Down Syndrome is an inherited condition. You cannot "get" Down Syndrome, it isn't contagious. A person is born with it.
It depends on how bad the down syndrome is
No, Down Syndrome is permanent.
There are signs that babies born to older moms are more likely to be afflicted, and in some countries there's a clear trend of women being older before having babies.
Angelman syndrome is a genetic disorder, as is Down syndrome. But they are not the same. Angelman Syndrome involves a deletion of Chromosome 15, whereas people with Down syndrome have an extra copy of Chromosome 21.
According to the Canadian Down Syndrome Society there are approx 35,000 Canadians with Down Syndrome.
Down Syndrome is caused by extra genetic material on Chromosome 21. About half of the children of people who have Down Syndrome are born with Down Syndrome themselves. See the Related Links below to view an article about the genetics of Down Syndrome.
No. Parents of Down Syndrome typically are normal genetically and there is no test for parents to determine the possibility of a Down Syndrome offspring. There are no known external factors that are known to contribute to Down Syndrome. It is possible to test for Down Syndrome in the fetus.
Well Down Syndrome is sometimes called Up Syndrome because most kids with Down Syndrome are very happy. Trisomy 21
yes. if that is true, then that means that down syndrome is genetic in your family. try researching it up. look it up on google. i highly reccomend wikepedia. the more you know, the more able you will be to understand these poor kids. allison386 Calling them "poor kids" is offensive. Down syndrome is a relatively common, and random, genetic variation--unless it is of the translocation type, which is a lot less common and is… Read More
down syndrome is not an emptional disorder
No, Barbara Walters does not have Down syndrome.
is down syndrome acquired genetic disease
No, because two males cannot have a child