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Cells work best at very specific pH's, too low or high and they will not function properly.

All living things are water-based systems, which means that they depend heavily on aqueous equilibria, especially acid-base equilibria. Therefore, all the acid-base and pH concepts we have discussed so far are extremely important to biochemistry, which is the study of the chemistry of biological systems.

Just as in other acid-base systems, biological macromolecules act as acids and bases by donating and accepting protons. However, due to the size of these molecules, they often contain several different groups that accept or donate protons instead of just one such group. Thus, we talk about macromolecules as having acidic and basic groups rather than as being acids and bases. These acidic and basic groups act as weak acids and bases, with Ka values which determine the extent of dissociation of the group depending on the pH of the system. Therefore, changes in the pH around the macromolecule will determine which groups are protonated and which are not, which in turn determines properties of the molecule. This is especially important for enzymes, which are proteins that act as catalysts for important biological reactions. Most enzymes only work within a certain pH range.

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11y ago
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7y ago

Organisms and the chemical reactions that make them living are affected by pH. Some do well in with an acidic pH and some do well in a basic pH situation. Humans cells do best with a pH of 7.4. If the level becomes too acidic or too basic, the proteins necessary for life (mainly enzymes) become inactivated. The cells will die and then the organism will die.

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13y ago

Your pH level effects almost everything. pH is a measure of the acidity of an aqueous solution. pH must be equal to 7. The pH scale ranges from 0 to 14.

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15y ago

because changes in pH have so many effects on the rates of chemical reactions, and it can, like temperature, make enzymes and the active sites inactive

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15y ago

What is the biochemical relevance of pH?

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Q: Why is pH an important issue of biology?
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