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Liquid oxygen contains 4,000 times more oxygen by volume than normal air. Materials that are usually considered non-combustible, (such as carbon and stainless steels, cast iron, aluminum, zinc and Teflon) may burn in the presence of liquid oxygen. Many organic materials can react explosively, especially if a flammable mixture is produced. Clothing splashed or soaked with liquid oxygen can remain highly flammable for hours.

In addition, liquid oxygen is very cold, and the cold alone can be hazardous to people, as well as embrittle materials that are not otherwise brittle so they could break more easily.

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