Karyotyping is a test to examine chromosomes in a sample of cells, which can help identify genetic problems as the cause of a disorder or disease. This test can:
Chromosome analysis
How the test is performedThe test can be performed on almost any tissue, including:
To test amniotic fluid, an amniocentesis is done.
A bone marrow specimen requires a bone marrow biopsy.
The sample is placed into a special dish and allowed to grow in the laboratory. Cells are later taken from the growing sample and stained. The laboratory specialist uses a microscope to examine the size, shape, and number of chromosomes in the cell sample. The stained sample is photographed to provide a karyotype, which shows the arrangement of the chromosomes.
Certain abnormalities can be identified through the number or arrangement of the chromosomes. Chromosomes contain thousands of genes that are stored in DNA, the basic genetic material.
How to prepare for the testThere is no special preparation needed.
How the test will feelHow the test will feel depends on whether the sample procedure is having blood drawn (venipuncture), amniocentesis, or bone marrow biopsy.
Why the test is performedThis test is usually done to evaluate a couple with a history of miscarriages, or to examine any child or baby who has unusual features or developmental delays that suggest a genetic abnormality.
The bone marrow or blood test can be done to identify the Philadelphia chromosome, which is found in about 85% of people with chronic myelogenous leukemia (CML).
The amniotic fluid test is done to check a developing fetus for chromosome abnormalities.
Normal ValuesAbnormal results may be due to a genetic syndrome or condition, such as:
This list is not all-inclusive.
Additional conditions under which the test may be performed:
The risks are related to the procedure used to obtain the specimen.
See:
In some cases, an abnormality may occur as the cells as growing in the lab dish. Karyotype tests should be repeated to confirm that an abnormal chromosome problem is actually in the body of the patient.
Special considerationsChemotherapy may cause chromosome breaks that affect normal karotyping results.
See also: Mosaicism
Your doctor may also order other tests that go together with a karyotype:
Karyotyping is a test to examine chromosomes in a sample of cells, which can help identify genetic problems as the cause of a disorder or disease. This test can:
Chromosome analysis
How the test is performedThe test can be performed on almost any tissue, including:
To test amniotic fluid, an amniocentesis is done.
A bone marrow specimen requires a bone marrow biopsy.
The sample is placed into a special dish and allowed to grow in the laboratory. Cells are later taken from the growing sample and stained. The laboratory specialist uses a microscope to examine the size, shape, and number of chromosomes in the cell sample. The stained sample is photographed to provide a karyotype, which shows the arrangement of the chromosomes.
Certain abnormalities can be identified through the number or arrangement of the chromosomes. Chromosomes contain thousands of genes that are stored in DNA, the basic genetic material.
How to prepare for the testThere is no special preparation needed.
How the test will feelHow the test will feel depends on whether the sample procedure is having blood drawn (venipuncture), amniocentesis, or bone marrow biopsy.
Why the test is performedThis test is usually done to evaluate a couple with a history of miscarriages, or to examine any child or baby who has unusual features or developmental delays that suggest a genetic abnormality.
The bone marrow or blood test can be done to identify the Philadelphia chromosome, which is found in about 85% of people with chronic myelogenous leukemia (CML).
The amniotic fluid test is done to check a developing fetus for chromosome abnormalities.
Normal ValuesAbnormal results may be due to a genetic syndrome or condition, such as:
This list is not all-inclusive.
Additional conditions under which the test may be performed:
The risks are related to the procedure used to obtain the specimen.
See:
In some cases, an abnormality may occur as the cells as growing in the lab dish. Karyotype tests should be repeated to confirm that an abnormal chromosome problem is actually in the body of the patient.
Special considerationsChemotherapy may cause chromosome breaks that affect normal karotyping results.
See also: Mosaicism
Your doctor may also order other tests that go together with a karyotype:
Review Date: 12/01/2010
Chad Haldeman-Englert, MD, Wake Forest University School of Medicine, Department of Pediatrics, Section on Medical Genetics, Winston-Salem, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
karyotyping
The karyotype is the number and appearance of chromosomes in the nucleus of a cell. Mature red blood cells don't have a nucleus, so they cannot be used for karyotyping.
Red Blood Cell
Karyotyping. Apex
Karyotype analysis is performed in cells undergoing mitosis, or cell division, in which the chromosomes condense and can be stained and visualized.
yes
karyotyping
Karotyping showed that the baby
ALL karyotyping
Because it has.
The karyotype is the number and appearance of chromosomes in the nucleus of a cell. Mature red blood cells don't have a nucleus, so they cannot be used for karyotyping.
You will have to ask them.
Red Blood Cell
By looking at the individuals chromosomes through a process called Karyotyping
yes
Karyotyping. Apex
Tay-Sach's has a defective gene on chromosme 15