Pellagra is not a vitamin, it's a disease.
It can be classed as either primary or secondary pellagra. Primary pellagra is typically caused by insufficient levels of dietary niacin, also known as vitamin B3 (exogenous production) or of the amino acid tryptophan, from which the body synthesizes niacin (endogenous production). It may result from decreased dietary intake, decreased nutrient absorption or increased nutritional requirements, or a combination of these factors. It may occur secondary to alcoholism, chronic gastrointestinal disease, carcinoid syndrome, or Hartnup disease, amongst a range of other conditions. Secondary pellagra is due to impaired amino acid conversion.
Pellagra is also frequently seen amongst populations that consume large quantities of corn and minimal animal protein, as corn is low in both niacin and biologically available tryptophan.
Catherine Convery Walsh
Registered Dietitian
MSc Human Nutrition and Metabolism, University of Aberdeen Medical School
Pellagra can be cured by taking nicotinamide. The nicotinamide can be found in pill form and will reverse the condition of pellagra.
he knew in the south every had pellagra
Pellagra is not an infectious disease. Pellagra is a nutritional deficiency disease.
Primary pellagra results when the diet is extremely deficient in niacin-rich foods.
Dr.Goldberger did an experiment to see what caused pellagra
Dr.Goldberger did an experiment to see what caused pellagra
Untreated pellagra will continue progressing over the course of several years, and is ultimately fatal.
The physician Dr. Gaspar Casal first described pellagra in the 18th century. However, the definitive link between diet and pellagra was made by Dr. Joseph Goldberger in the early 20th century.
The 4 D's of pellagra are dermatitis (skin rash), diarrhea, dementia (mental confusion), and ultimately death if left untreated. Pellagra is caused by a deficiency of niacin (vitamin B3) in the diet.
pellagrophobia
yes
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