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Oxygen is reactive because it needs to gain two more electrons to fill its outermost shell while neon's outermost shell is completely full of electrons.

In more technical terms, neon has an octet of electrons whcih makes it inert. Neon forms no known compounds. Oxygen has 6 valence electrons and reacts to "achieve" the octet. This can be by either forming ionic bonds where it gains two electrons to form the oxide ion, O2- or covalently where it shares electrons, as in water H2O where oxygen has shares two electrons with each hydrogen.

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Betty Tromp

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3y ago

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