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It depends on the substance, since mg is a measure of mass and ml is a measure of volume. If you are talking about water, then a gram, or 1000 milligrams (mg) makes a millilitre (ml); so 25 mg would be .025 of a ml. But if you are measuring Mercury, much denser than water, 25 mg would have a smaller volume; 25 mg of petroleum would be a slightly larger volume.

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