Does smoking oxycodone show up on a drug test?

Answer 1

Yes. Oxycodone is prescribed for the relief of moderate to high pain under the well-known pharmaceutical trade names of OxyContin®, Tylox®, Percodan® and Percocet®. While Tylox, Percodan and Percocet contain only small doses of oxycodone hydrochloride combined with other analgesics such as acetaminophen or aspirin, OxyContin consists solely of oxycodone hydrochloride in a time-release form.

While classified as an Opiate, the chemical structure and metabolite of Oxycodone requires a separate Opiate test with a substantially higher sensitivity detection level than that of the standard Opiate drug test. Consequently, a positive test result will not only confirm Oxycodone but other opiates as well. In this regard the Oxycodone test is not Oxycodone specific but opiate specific, being able to detect Oxycodone/opiate use at the higher sensitivity level required while the 2000 ng/ml sensitivity level of the standard opiate test would not detect Oxycodone.

Oxycodone is known to metabolize by demethylation into oxymorphone and noroxycodone. In a 24-hour urine, 33-61% of a single, 5mg oral dose is excreted with the primary constituents being unchanged drug (13-19%), conjugated drug (7-29%) and conjugated oxymorphone (13-14%)1. The window of detection for oxycodone in urine is expected to be similar to that of other opioids such as morphine.

Oxycodone is a semi-synthetic opioid with a structural similarity to codeine. The drug is manufactured by modifying thebaine, an alkaloid found in the opium poppy. Oxycodone, like all opiate agonists, provides pain relief by acting on opioid receptors in the spinal cord, brain, and possibly directly in the affected tissues.

Answer 2

Yes, it will show up as positive for opiates in a urine toxicology screen.

Answer 3

It will not show in a normal urinalysis but it can show up in a urine toxicology screen as an opiate 24-72 hours max after your last use.