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The half-life of the drug is the time taken for the plasma concentration of the drug to reduce to 50% of its original value.

Units of half life are hour, minute, or day.

The formula for calculation half life of a drug is as follows:

Cp is the concentration at time one and Cp/2 is the concentration at time one half-life later:-

In( Cp/2) = In Cp - Kel . t1/2

half life of the drug (t 1/2) = 0.693/kel

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