Depending on the illness, disease, or condition that put a patient in ICU to begin with, uncomplicated ICU psychosis is usually totally reversable. The cause must be determined, including review of all medications and their side effects. If a medication may have induced hallucinations, an alternative medication should be used. Nurses should continually reassess the patient's mental status and report changes to the physician.
Sometimes, the patient is so ill from the original problem that the best course of action is to treat the psychosis without withdrawing a suspected medication, in cases where the suspected medication is deemed vital to the patient's physical recovery.
Also, it's easy to become disoriented as a patient in an ICU. There are usually no windows, no indication whether it is day or night, sleep may be frequently interrupted or the patient loses days due to sedation, and other factors all contribute to disorienation and short-term psychosis.