Congenital myasthenic syndromes are a group of related disorders
caused by inherited defects in the acetylcholine receptor.
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Lambert-Eaton myasthenic syndrome is an autoimmune disease that
causes muscle weakness and easy fatigability, particularly in the
pelvic muscles and thighs.
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Family history of Lambert-Eaton myasthenic syndrome is a known
risk factor for development of the disease, as is a personal
history of smoking
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Patients who develop Lambert-Eaton myasthenic syndrome should be
thoroughly screened for the presence of a previously undetected
cancer
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Patients with Lambert-Eaton myasthenic syndrome should be
examined and then treated by both a neurologist and an appropriate
cancer specialist (oncologist).