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Attenuated simply means "weakened". Vaccines made with attenuated pathogens, such as the flu virus in flu nasal mist vaccines in the US, work like any vaccine to trigger an immune response so that your body builds up antibodies to be immune to the virus (or whatever pathogen is intended to be prevented). Flu vaccines made for injection, for example, are made with inactive viruses that are either "dead" or are pieces of the virus that are incomplete so they can not cause disease but can trigger the proper immune response and antibody development. Other vaccines, like the flu nasal mist, use whole, "live" viruses in the vaccine preparation to get a better response and, in those vaccinations, the live viruses are weakened so that they can not make you ill but can cause the proper immunity to be developed.

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Viruses are attenuated by changing them a little. They can be part of a vaccine and be given and not cause the disease but cause the body to make antibodies against the non-attenuated virus. If the person get that non-attenuated virus, the body is ready to "ambush" it.

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Q: How are viruses attenuated?
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Related questions

What is injection of weakened viruses is called?

A vaccination using a vaccine made from attenuated live viruses.


What are solutions of killed or weakened viruses?

One such example would be a vaccine for viral illnesses. They can be made from attenuated (weakened) viruses or from inactivated viruses or pieces of them.


What is attenuated flu vaccine?

Attenuated simply means "weakened". An attenuated flu vaccine refers to vaccines made with live viruses (so you get a good immune response), but they have been weakened chemically so that they are unable to give you the flu. There are two types of flu vaccines available in the US. What is called inactivated, inactive or "dead" vaccine and what is called "live", weakened/attenuated vaccine. The injectable vaccines (intradermal and intramuscular) are made with "dead" viruses and the nasal spray is made with "live" attenuated viruses.


What is a vaccine that contains live weakened pathogens?

They are called live attenuated vaccines. Attenuated means weakened. The nasal mist flu vaccine is an example of a live attenuated vaccine. The vaccines for flu that are injected are made from pieces of viruses or "dead" viruses. See the related question below for more information on these two types of vaccines.


Are the microbes that are injected in a vaccination dead or alive?

They can be either. Some vaccines are made with dead viruses or particles of viruses and other vaccines are made with attenuated (weakened) viruses that are not able to make an otherwise healthy person sick. In 2009 the swine flu vaccine approved for use in the US was prepared both ways, the nasal flu vaccine was made from attenuated viruses and the shots were made with dead viruses.


What are substances made from dead viruses?

Vaccines for the prevention of the specific viral infection can be made with inactive "dead" viruses. They are also made with live, but attenuated (weakened), viruses. See more below about vaccines.


Can Gardasil cause HPV?

No. This is not possible. The Gardasil vaccine contains recombinant proteins from HPV to provoke an immune response. There are no live viruses, attenuated viruses or even dead viruses in the vaccine. The viral DNA is not present in any form.


Which vaccine contains weakened?

They are called attenuated vaccines. Attenuated means weakened, they do this usually with chemicals and then the attenuated viruses are not able to make you sick, but they are strong enough to trigger the immune response to provide immunity.An attenuated virus. Attenuated simply means weakened. For example, you will see references to this in regard to the flu vaccines. This is also abbreviated when talking about the flu vaccines as LAIV, Live Attenuated Influenza Vaccine.That is a good description of what a vaccine is, although some other substances also could be described similarly. The weakened or killed virus in a vaccine is non-threatening to most people. It can be a problem for infants under six months old, some children and adults with under-developed immune systems or who have immune system disorders.


When you get a vaccine can you get the virus?

There are a few circumstances that can create some risk of getting the virus, such as in people whose immune systems aren't working right (e.g., they recently had cancer chemotherapy or HIV or some other immuno-suppressive disorder). See the list of people in the related question below who should not get vaccinated with the types of vaccines that contain a live "attenuated" virus. Attenuated means weakened. When someone has a weak immune system, they may be susceptible to the weakened form of virus in the vaccine. But they would not be able to be sick from getting vaccines that contain "dead" viruses. With the flu vaccines, for example, the shots have dead viruses in them but the nasal mist has live attenuated viruses in it.Sometimes. If the vaccine is a live attenuated (weakened) vaccine, then you get a dose of virions (viral particles/viruses) that are no longer dangerous to humans as they have been weakened so they can not make you sick. Other vaccines (such as Gardasil) are made with Virus-like particles (VLP) and these are just pieces of the virus (such as the envelope) not actually working and replicating viruses so they can not make you sick either.


How do live attenuated vaccines work?

They are vaccines that contain viruses that have been treated to make them too weak to make you sick. The word "attenuated" just means "weakened". This type of live attenuated vaccine is what is approved for intra-nasal administration (nasal spray) of the flu vaccines in the US. The approved intra-muscular injection vaccine is made with totally inactivated ("dead") virus particles. See related questions below.


Which types of matter can be attenuated?

None. Light and sound waves can be attenuated, but not matter.


What is used to make the measles vaccine-?

The active ingredient is the live, attenuated (weakened) measles virus.