The driving distance between Miami, FL and Key West, FL is approximately 160 miles. The driving time would be approximately 3 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
158 miles taking U.S. 1 SOUTH.
160 MILES
163 miles - about 3 hours 50 mins by car!
165 miles
It takes 3.5 hours to drive up US1 to Miami.... about 130 miles to Miami KIRA WAS HERE 09/18/14
Depending where in Miami your traveling from. But the drive on average is 45 mintues to an hour.
By car, it's about 159 miles.
how should i know
The Keys are 120 miles long. Miami to Key West is 159 miles.
29 miles
It is 160.34 miles according to MapQuest.
189 miles