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If using powdered formula it is usually 1 scoop (provided in can) per two ounces of water.

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Q: How much formula do you need to put in a baby's bottle?
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Preparing a Baby Bottle Safely with Similac Formula?

New moms may be inexperienced in the art of preparing baby bottles. When your infant becomes hungry, you will want to be prepared with a clean bottle with formula at just the right temperature. Similac formula is often recommended by pediatricians to mothers who prefer to bottle feed. Preparation and formula handling can be quite simple once you understand the basics.Boil WaterBring a pan of water to a rolling boil for one minute, and then turn off the heat. Pour the desired amount of water into the bottle, and allow it to cool to room temperature before adding the formula. Adding the formula to boiling water can cause clumps and reduce the nutritional value. Ask your pediatrician if you need to boil bottles, nipples, rings, and utensils.Mix FormulaAlways wash your hands with warm water and soap before handling formula and newly washed bottles. Measure and pour the desired amount of Similac formula into the bottle of water. As directed on the formula package, use an unpacked, level scoop(s) when adding the formula. Replace the cap on the bottle and shake. Feed the formula immediately to the infant.Warm FormulaWhile formula does not always need to be warmed up before a feeding, some infants and mothers prefer a warm bottle. Never microwave a bottle, as this can cause "hot spots" that could burn your baby. Once the bottle is prepared, set it inside a bowl of warm water. Alternatively, hold the bottle under warm tap water. Always test the formula before feeding to baby.Store FormulaStoring formula properly is very important to avoid the build-up of bacteria. Once powdered formula has been opened, the container should be closed and stored in a dry, cool area not in a refrigerator. Use the contents of the container within one month, and avoid extreme temperatures. Once the formula has been mixed with water, feed it immediately to the baby or store in the refrigerator in a sealed container. Use the formula within 24 hours.Preparing Similac formula the correct way can lead to a healthy and happy baby. Always follow the instructions on the formula package, and talk to your pediatrician about any problems you may have with the formula.