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Yes and no. Hydrocodone 5-325 and 5-500 contain the same amount of Hydrocodone but 5-325 contains less acetiminophen. Wheras the 5-500 contains 5 mg of hydrocodone and 500 mg of acetiminophen, the 5-325 contains 5 mg of hydrocodone and 325 mg of acetiminophen. The 5-325 is better for you.

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14y ago
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12y ago

No. Vicodin is comprised of both hydrocodone and acetaminophen (Tylenol). The 5 refers to the number of milligrams of hydrocodone are in the pill, and the other numbers refer to how much acetaminophen is in the pill.

The 5/325 has 5mg of hydracodone and 325 of acetaminophen. The 5/500 has the same amount of hydacodone, but more acetaminophen.

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Q: Is hydrocodone 5-325 the same as hydrocodone 5-500?
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