Hades and the loss of her daughter, Persephone
Hades because he took persephone
Persephone, as Queen of the Underworld, was a deity of death, to draw her attention was to invite death as the Greeks thought it.
The Goddess Demeter fears the God of the underworld who had kidnapped her daughter, Persephone!
One would imagine that the Queen of the Underworld and goddess of Spring would not have much to fear. Indeed, more often then not, she induces fear.
Persephone, being the daughter of Zeus the king of the gods, of Hades the king of the Underworld and the niece of Poseidon the sea king did not have any enemies that would survive insulting her if they did not fear the ancient Greek goddess Persephone for her self - which many did.
Persephone was the daughter of Demeter, while Melinoe was the daughter of Persephone and Zeus. This made Persephone Melinoe's mother. In some versions of Greek mythology, Melinoe was associated with ghosts and the underworld, reflecting her parentage as the daughter of Persephone, who was queen of the underworld.
Persephone enemy was Methane because she slept with Persephone's husband, Hades.
Persephone's mother was Demeter. Persephone's brother was Zeus, who was also Persephone's father (confusing but is correct in the myth)
Persephone's mother was Demeter. Persephone's brother was Zeus, who was also Persephone's father (confusing but is correct in the myth)
Persephone has no children.
No, Persephone is not single.