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Complement is a protein made in the innate immune system that embeds itself in the membrane of bacteria, leaving a hole through which the cytoplasm escapes killing the bacterial cell.
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∙ 7y ago
Wiki User
∙ 12y agoIt is part of the immune system.
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What is the role of complement system in immune response?
The role of a complement system in immune response is to make sure that no bad cells penetrate the immune system. A complement system of immunization might be a series of shots, like booster shots for immunizations.
What is C3 convertase?
Humans have both an "innate" and an "adaptive" immune system. There are a number of proteins circulating in the blood as part of the complement system that belongs to the innate immune system (although the adaptive system can activate it as well). Normally, the complement proteins are inactive. When the immune system detects some threat, the complement system is triggered and the circulating proteins are chemically split into smaller components. C3 convertases are chemicals that cleave C3 complement into breakdown products in both the "classical" and the "alternative" pathways of the complement system.
What plasma proteins are complement proteins?
Complement proteins are a series of immune proteins that carry out complement cascade reactions. These proteins are helping the immune system to lean up from the cells. complement proteins are not antibodies.
What is the immune disorder that occurs when the production or activity of immune cells or complement is abnormal?
The immune disorder that occurs when the production or activity of immune cells or complement is abnormal is called primary immunodeficiency. It is a group of genetic disorders that affect the immune system's ability to effectively defend the body against infections. This can lead to recurrent or severe infections and other immune-related complications.
What system involves plasma proteins activated when they contact a bacterial cell?
The complement system is made up of a large number of plasma proteins. They react with one another to opsonize pathogens and induce a series of inflammatory responses that help to fight infection.
How does the innate immune system interact with the adaptive immune system?
The complement system is a series of about 20 proteins that are involved in a cascade effect during an immune response. Complement is generally divided up into 3 pathways: classical, lectin, alternate. The classical pathway involves a complement protein binding to an antigen-antibody complex (and thus its role in adaptive immunity). Whereas in the alternate pathway, complement (C3) binds directly to the foreign cell( usaully bacteria). Thus its repsonse is non specific and therefore is also part of the innate imune system.
What are complement deficiencies?
Complement deficiencies are a group of disorders in which there is a reduced level of specific proteins, complement, involved in proper immune functioning.
Which immune response would not occur when staphylococcus aureus enters the bloodstream?
The specific immune response that may not occur when Staphylococcus aureus enters the bloodstream is the activation of the complement system. This response involves a series of proteins that help to eliminate invading microorganisms, but certain strains of Staphylococcus aureus possess proteins that can inhibit or evade complement activation, allowing the bacterium to evade immune detection and destruction.
What system protects the body against infection?
your immune system and your White blood cells produce antibodies
Specialized disease-fightning proteins are?
Proteins involved mainly in defense system are antibodies or immunoglobulins.They help to neutralize the pathogen and clear them out of the cells. In addition there are complement proteins, Interferons, cytokines, etc. in the immune system.
How dangerous are recurring episodes of meningococcemia?
Certain people with immune system defects (particularly those with defects in the complement system) may have recurrent episodes of meningococcemia. These patients, however, seem to have a less serious outcome.
What is the pathophysiology of septicemia?
Septicemia is the presence of pathogenic bacteria in the bloodstream. Once the bacteria enter the bloodstream, the innate immune system is triggered and starts the complement cascade. This then causes the symptoms of acute infection (fever, malaise, dehydration, fatigue). Depending upon the specific bacteria and the host's immune system, the humoral immune system may also kick into gear, producing antibodies against the invading bacteria.
