some weapons have damage bonuses to certain types of enemies or magic bonuses such as extra fire damage, but in terms of just straight up damage, most powerful weapon (not including any DLC) is the greatsword Ageless.
it all depends on what type of character you have
for a warrior you can have dual wielding, 2h and weapon and shield
dual wielding i would recommend keening blade or topsiders honor, if you have dlc i would recommend starfang
2h depends on if you like swords, axes or hammers, for swords, i would recommend starfang(you can get 2h version) or the summer sword, for axes probably the biteback axe obtained by killing the high dragon and for hammers i would go for chasind great maul. keep in mind the chasind great maul has 14.4 damgage but also has a +5 damage bonus making it the best 2h weapon with its high armour penetration.
Use amour and weapon and attack it.
the most powerful weapon is the lost katana it is +110
you can get a powerful darkness weapon in faclonreach by going right 2 times, up then talk to the mysterious stranger and buy the staff weapon for 28000
From chests,weapon stands,defeated enemies corpses or you can buy them from shops
either get a doom weapon worth 28000 or join rare seasonal wars they always give the most powerful and rare weapons
Have Aegis as your guest.Ghange your dragon element to Light (or Ice) and have a good Light (or Ice) weapon. Note:Use Ice element on your dragon and on weapon only if enemy is powerful and you need to use Ice Domain(from Aegis).
Save up for a Doom Weapon. It costs 28,000 coins from the mysterious stranger that is west of falconreach. It is a lv 8 weapon but it hits 35-52 Darkness.
because in the nijago universe the strongest of all creatures are the dragons, and the most powerful type of dragon is the FIRE dragon. Legend of Zelda rules, thank you and goodnight.
you just use puriphy the first doom wepon
The labor union's most powerful weapon is the strike.
If by "bomb" you mean a conventional explosive weapon, then the nuclear weapon is more powerful.
Deadpool