Primary structure: the amino acid residues attached to each other by peptide bonds. These are formed by hydrolysis. When an amino acid is in at pH of 7, the carboxyl group will have a negative charge (COO-) and the amine group will have a positive charge (NH3+). This is called the zwitterion form. The amino acids will undergo hydrolysis where the amine group will give up two of its hydrogen atoms and the carboxyl group will give up one of the oxygen. These will form water, while the carbon from the carboxyl group and the nitrogen from the amine group will form a single bond. The alpha carbons (#1 chiral carbons) from each amino acid, the carboxyl carbon and oxygen, the hydrogen and nitrogen from the amine group will all be planar at this point. The peptide bond is the C=O and the N-H.
Secondary structure: The most commonly found are the alpha helices and beta sheets. These are held together by hydrogen bonding. A great example is DNA. The purines and pyridines form hydrogen bonds with each other and create the helix from two single strands of primary structure.
Tertiary structure: When the R groups of amino acids interact with one another, tertiary structure occurs. It is the folding of the protein. Disulfide bonds are a great example of how tertiary structures form. Disulfide bonds need two cysteine amino acids to form.
Quaternary structure: Several (more than two) tertiary structures join to form the quaternary structure. Don't be fooled by the name, it can be more than four folded proteins. Hemoglobin is a four tertiary structure protein with two alpha and two beta subunits.
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primary protein structure
The sequence of amino acids affects protein function. The three-dimensional structure of a protein determines its function. The three-dimensional structure of a protein is determined by the sequence of its amino acids.
Primary structure of the protein is simply its amino acid sequence. It is the sequence in which amino acids are added during protein synthesis.
Is the sequence of amino acids that form the protein
polypeptide chain
The monomers in a polypeptide are the amino acids. The sequence of amino acids in a polypeptide (or protein) is called the primary structure. It is the primary structure of proteins which is coded for by the DNA in the genes: the sequence of bases in the DNA is a code for the sequence of amino acids in a protein (or polypeptide). See: http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/PrimaryStructure.html http://staff.jccc.net/PDECELL/biochemistry/protstruc.html
The sequence of amino acids affects protein function. The three-dimensional structure of a protein determines its function. The three-dimensional structure of a protein is determined by the sequence of its amino acids.
Primary structure of the protein is simply its amino acid sequence. It is the sequence in which amino acids are added during protein synthesis.
Peptide sequence or amino acid sequence is the order in which amino acid residues, connected by peptide bonds, lie in the chain in peptides and proteins. The sequence is generally reported from the N-terminal end containing free amino group to the C-terminal end containing free carboxyl group. Peptide sequence is often called protein sequence if it represents the primary structure of a protein.
DNA determines the sequence of the amino acids (building blocks) in a protein. The sequence of nitrogen bases in the DNA determines the sequence of amino acids in a protein.
The number and sequence of amino acids
Primary - the sequence of amino acids that make up a protein
Is the sequence of amino acids that form the protein
No, the polypeptide sequence of amino acids is the primary structure of a protein. The quaternary structure of the protein is the non-covalent interactions (hydrophobic binding, van der wals forces etc..) between subunits/domains of a protein.
Yes. The sequence of nitrogen bases in DNA determines the sequence of amino acids in a protein. The sequence of amino acids determines the structure and function of a protein.
The sequence of amino acids determines the specific function of a protein. The shape and structure of the protein determines where in the cell it can go.
polypeptide chain
Amino acids, the building blocks of proteins.