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When did Banting and Best use insulin for the first time?

Updated: 8/17/2019
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15y ago

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January 11th 1922 the first injection was made on Leanard Thompson, a 14-year-old diabetic. But it didn't work, so they worked on it for some time and then on 23rd they made the second injection and it work, with no side effects.

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Q: When did Banting and Best use insulin for the first time?
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Related questions

Who invented insulin for the first time?

Fredrick Banting was the original inventor of insulin


Who is insulin founder?

Dr. Fredrick Banting, Charles Best (a medical student at the time of the discovery), Professor J. J. R. Macleod and Dr. James Collip.


Banting and best?

Banting was an out-of-work doctor/surgeon and Best a medical student in Toronto. The problem with isolating insulin (which controls the blood sugar level) was that the pancreas contained enzymes that destroyed the insulin if it was cut out. Banting had the idea of ligaturing the pancreas in situ so that it withered away leaving the insulin largely unaffected. He employed Best (a doctor's son) to help with the surgery and look after the dogs on which it was done with the permission of the University Professor in charge of the department. I think he was called McLeod (anyway he was a Scot). The experiments were carried out during the summer vacation under hot inclement conditions in a garret room, but they worked. The Nobel prize was given to Banting and McLeod (just because he was head of department and although he was not involved in the research in any way) but not to Best who did all the nasty work. It was said that, as a mere student, he was too young to receive an award. However, he did ultimately become head of department. I was in Toronto fairly soon after his death and was shown his office by his secretary who said that he was a really nice man. So he did win after all. I should mention that there had been numerous attempts to isolate insulin by the more traditional biochemical methods of isolation and extraction of the pancreas but all had failed. So it was a signal achievement as well as one that was put to practical use in saving lives in the shortest possible time. It would not happen today!!


What was Banting and Best's scientific research?

Banting was an out-of-work doctor/surgeon and Best a medical student in Toronto. The problem with isolating insulin (which controls the blood sugar level) was that the pancreas contained enzymes that destroyed the insulin if it was cut out. Banting had the idea of ligaturing the pancreas in situ so that it withered away leaving the insulin largely unaffected. He employed Best (a doctor's son) to help with the surgery and look after the dogs on which it was done with the permission of the University Professor in charge of the department. I think he was called McLeod (anyway he was a Scot). The experiments were carried out during the summer vacation under hot inclement conditions in a garret room, but they worked. The Nobel prize was given to Banting and McLeod (just because he was head of department and although he was not involved in the research in any way) but not to Best who did all the nasty work. It was said that, as a mere student, he was too young to receive an award. However, he did ultimately become head of department. I was in Toronto fairly soon after his death and was shown his office by his secretary who said that he was a really nice man. So he did win after all. I should mention that there had been numerous attempts to isolate insulin by the more traditional biochemical methods of isolation and extraction of the pancreas but all had failed. So it was a signal achievement as well as one that was put to practical use in saving lives in the shortest possible time. It would not happen today!!


How old was Frederick Banting at death?

Frederick Banting died on February 21, 1941. He was a fighter plane pilot and his plane got shot down in Newfoundland.


Who found the treatment for diabetes?

The function of the pancreas was discovered as early as 1869 by Paul Langerhans, a German student of medicine. Georg Ludwig Zuelzer was the first person that actually treated dogs with an impure form of insulin. He was not the first to discover the function of pancreas but he is considered the first to actually move on and actually try it out on dogs. This happened in 1906. He did however not finish his work. The first actual injection of insulin happened 11 January 1922. It was not pure enough and the boy who got it had strong allergic reactions. 12 days went past with work and then the boy received another injection, and this time it was successful. Macleod and Banting was awarded the Nobel-price i physiology and medicine in 1923. They managed to produce Insulin of sufficient purity and quantity the year before, and production took place.


What is the peak time when administering regular insulin and NPH insulin?

the peak time for Regular insulin is 4 hours and the peak time for NPH is 8 hours. I take both of them.


What happens in there is over secretion of insulin?

If there is overproduction of insulin then your sugar is low all the time. You will be hypoglycemic all the time.


What will happen if you draw cloudy insulin up first then clear insulin and give to a patient?

The "cloudy" insulins are long-acting, while the "clear" insulins are rapid or short-acting. Drawing up the clear insulins first prevents the vial of short-acting insulin from being contaminated with a long-acting insulin.


Why is cow insulin a good substitue for human insulin?

Insulin from pigs or cows can cause immune reactions in some people, or people may develop an allergy to the insulin over time and it will be ineffective. Human insulin is not immunogenic and so is preferred.


Does insulin affect your reaction time?

Yes!


Who is Charles Banting?

there is no such person as Charles banting. you are probably getting confused by Fredrick banting and his assistant DR. Charles. its a common mistake. RETARD ____ i believe you are wrong, there IS a Charles Banting in fact, he exists in this generation if you don't believe me, go on facebook and search the name Charles Banting i will prove you wrong! if you are still in denial after searching for this person, YOU SIR are the retard! i don't know the dude, but i heard he is a pretty cool guy talk to the dude, because after seeing your answer, i talked to the guy. how you ask??? well i know him from a friend who has been telling me stories about the dude, ive talked to him but not for a long time, during our short conversation, i found that he IS a nice guy if you don't have facebook, please make one for the sake of your research or probably you have no friends... Good Day to You Sir ___ lmfao wow ____ i am not lying i can give you a link to the dudes facebook if you want ____ I KNOW this person. In fact, I'm talking to him on skype right now. Therefore Charles Banting does indeed exist.