| 221 BC by topic | |
| Politics | |
| State leaders – Sovereign states | |
| Birth and death categories | |
| Births – Deaths | |
| Establishments and disestablishments categories | |
| Establishments – Disestablishments | |
| Gregorian calendar | 221 BC |
| Ab urbe condita | 533 |
| Armenian calendar | N/A |
| Assyrian calendar | 4530 |
| Bahá'í calendar | -2064–-2063 |
| Bengali calendar | -813 |
| Berber calendar | 730 |
| English Regnal year | N/A |
| Buddhist calendar | 324 |
| Burmese calendar | -858 |
| Byzantine calendar | 5288–5289 |
| Chinese calendar | 己卯年 (2416/2476) — to —
庚辰年(2417/2477) |
| Coptic calendar | -504–-503 |
| Ethiopian calendar | -228–-227 |
| Hebrew calendar | 3540–3541 |
| Hindu calendars | |
| - Vikram Samvat | -164–-163 |
| - Shaka Samvat | N/A |
| - Kali Yuga | 2881–2882 |
| Holocene calendar | 9780 |
| Iranian calendar | 842 BP – 841 BP |
| Islamic calendar | 868 BH – 867 BH |
| Japanese calendar | |
| Julian calendar | |
| Korean calendar | 2113 |
| Minguo calendar | 2132 before ROC 民前2132年 |
| Thai solar calendar | 323 |
| Wikimedia Commons has media related to: 221 BC |
Year 221 BC was a year of the pre-Julian Roman calendar. At the time it was known as the Year of the Consulship of Asina and Rufus/Lepidus (or, less frequently, year 533 Ab urbe condita). The denomination 221 BC for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.
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