(medicine) Any thickening of the prickle-cell layer of the epidermis; associated with many skin diseases.
An increase in the thickness of the prickle cell layer of the epidermis; hyperacanthosis.
ac'an·thot'ic (-thŏt'ĭk) adj.
An increased thickness of the stratum spinosum, due to either an increased number or hypertrophy of cells.
An increase in the number of cells in the prickle cell layer of stratified squamous epithelium, with thickening of the entire epithelial cell layer and a broadening and fusing of rete pegs.