acanthosis

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(a′kan′thō·səs)

(medicine) Any thickening of the prickle-cell layer of the epidermis; associated with many skin diseases.


(ăk'ăn-thō'sĭs, ăk'ən-)
n., pl. -ses (-sēz').

An increase in the thickness of the prickle cell layer of the epidermis; hyperacanthosis.

ac'an·thot'ic (-thŏt'ĭk) adj.

An increased thickness of the stratum spinosum, due to either an increased number or hypertrophy of cells.

  • frictional a. — see acanthosis nigricans (below).
  • a. nigricans — a skin disease of dogs characterized by hyperpigmentation, lichenification, seborrhea, and alopecia commencing in the axillae and often spreading to involve flexural surfaces of all limbs, and the ventral body. Dachshunds are particularly predisposed to primary acanthosis, often developing the first changes at a young age. Sporadic cases are secondary to systemic disease, endocrinopathies, hypersensitivity reactions and friction in body folds.
(ak′ənthō′sis)
n

An increase in the number of cells in the prickle cell layer of stratified squamous epithelium, with thickening of the entire epithelial cell layer and a broadening and fusing of rete pegs.

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