Share on Facebook Share on Twitter Email
Answers.com

acetamide

 
Dictionary: a·cet·a·mide
(ə-sĕt'ə-mīd', ăs'ĭt-ăm'īd') pronunciation
n.
The crystalline amide of acetic acid, CH3CONH2, used as a solvent and wetting agent and in lacquers and explosives.


Search unanswered questions...
Enter a question here...
Search: All sources Community Q&A Reference topics
Chemistry Dictionary: ethanamide
Top

Variant: acetamide

A colourless solid crystallizing in the form of long white crystals with a characteristic smell of mice, CH3CONH2; r.d. 1.159; m.p. 82.3°C; b.p. 221.25°C. It is made by the dehydration of ammonium ethanoate or by the action of ammonia on ethanoyl chloride, ethanoic anhydride, or ethyl ethanoate.



WordNet: acetamide
Top
Note: click on a word meaning below to see its connections and related words.

The noun has one meaning:

Meaning #1: a colorless solid amide of acetic acid used as a solvent and in the synthesis of organic compounds
  Synonym: ethanamide


Wikipedia: Acetamide
Top
Acetamide
Acetamide-2D-skeletal.png
Acetamide-3D-balls.png
IUPAC name
Identifiers
CAS number 60-35-5 Yes check.svgY
PubChem 178
SMILES
InChI
InChI key DLFVBJFMPXGRIB-UHFFFAOYAC
ChemSpider ID 173
Properties
Molecular formula C2H5NO
Molar mass 59.07 g mol−1
Density 1.16 g/cm³
Melting point

79-81°C

Boiling point

222 °C

Solubility in water 2g/1ml
Hazards
MSDS External MSDS
EU Index 616-022-00-4
EU classification Harmful (Xn)
Carc. Cat. 3
R-phrases R40
S-phrases (S2), S36/37
NFPA 704
NFPA 704.svg
1
3
1
 
 Yes check.svgY (what is this?)  (verify)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Acetamide (or acetic acid amide or ethanamide), CH3CONH2, the amide of acetic acid, is a white crystalline solid in pure form. It is produced by dehydrating ammonium acetate:[1]

CH3COONH4 → CH3CONH2 + H2O

It is used as a plasticizer and in the synthesis of many other organic compounds.

Acetamide is not extremely combustible, but releases irritating fumes when ignited. It is toxic by inhalation (of dust), ingestion, skin and eye contact. Skin or eye contact may cause redness and pain.

The derivative N,N-dimethylacetamide (DMA), which has two methyl groups replacing the amine protons, is used as a solvent. N-methylacetamide is often used as the simplest model in studies of the peptide bond.

Recent work on the Robert C. Byrd Green Bank Telescope has resulted in the discovery of several organic (carbon-based) compounds near the center of the Milky Way galaxy. Acetamide has been detected. This is particularly important as acetamide has an amide bond, similar to the essential bond between amino acids in proteins. This supports the theory that organic molecules that can lead to life (as we know it on Earth) can form in space.

In addition, acetamide is rarely found on burning coal dumps, as a mineral of the same name.[2][3]

Cancer link

Acetamide has been found to cause cancer in laboratory animals. It is classified in Group 2B "possible human carcinogen" by the IARC.

References

  1. ^ G. H. Coleman and A. M. Alvarado (1941), "Acetamide", Org. Synth., http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv1p003 ; Coll. Vol. 1: 3 
  2. ^ http://www.mindat.org/min-13.html Mindat.org
  3. ^ http://rruff.geo.arizona.edu/doclib/hom/acetamide.pdf Handbook of Mineralogy
  • J. M. Hollis, F. J. Lovas, Anthony J. Remijan, P. R. Jewell, V. V. Ilyushin, and I. Kleiner (2006). "Detection of Acetamide (CH3CONH2): The Largest Interstellar Molecule with a Peptide Bond". The Astrophysical Journal 643 (2): L25–L28. doi:10.1086/505110. 

External links


 
 

 

Copyrights:

Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.  Read more
Chemistry Dictionary. A Dictionary of Chemistry. Sixth Edition. Copyright © Market House Books Ltd, 2008. All rights reserved.  Read more
WordNet. WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Acetamide" Read more