Active ingredient

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  • Genres: Jazz

Biography

In the late 1980s and early 1990s, it seemed as though Active Ingredient had the potential to become the Jazz Messengers of fusion. In fact, the band's concept was similar to that of drummer Art Blakey's Jazz Messengers -- lineups would change, and the idea was to feature young, undiscovered talent rather than established artists. One key difference, however, was the fact that unlike Blakey, Ingredient leader/producer Steve Rucker didn't actually play on his band's albums. A drummer who played around South Florida a lot, Rucker founded Ingredient at the University of Miami (where he was a faculty member) in 1987. Having boasted such talented alumni as Pat Metheny, Danny Gottlieb, Mark Egan and the late Jaco Pastorius, The University's jazz program had a reputation for being very fusion-friendly. Ingredient came to be known as the "Fusion Ensemble" on campus and was comprised of Rucker's students. The band debuted on Bainbridge with 1988's Building Houses, followed by Extra Strength in 1990. Being "The Jazz Messengers of Fusion" (this critic's words, not Rucker's) was a wonderful idea, but unfortunately, Ingredient never became as well-known nationally as it deserved to be. ~ Alex Henderson, Rovi
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Active ingredient

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An active ingredient (AI) is the substance in a pharmaceutical drug or a pesticide that is biologically active. The similar terms active pharmaceutical ingredient (API) and bulk active are also in medicine, and the term active substance may be used for pesticide formulations. Some medications and pesticide products may contain more than one active ingredient. The traditional word for the API is pharmacon or pharmakon (from Greek: (φάρμακον), adapted from pharmacos) which originally denoted a magical substance or drug.

A dosage form : the API, which is the drug itself; and an excipient, which is the substance of the tablet, or the liquid the API is suspended in, or other material that is pharmaceutically inert. Drugs are chosen primarily for their active ingredients. Because homeopathic products no longer have any biologically active ingredients, their list of ingredients refers to the original ingredients used in their preparation and the finished product no longer contains any active ingredients.

Contents

Pharmaceuticals

Patients often have difficulty identifying the active ingredients in their medication, and are often unaware of the notion of an active ingredient. When patients are on multiple medications, active ingredients can interfere with each other, often resulting in severe or life-threatening complications.[1] There now exist online services which can identify the active ingredient of most medications, such as the Medicine Name Finder developed by the National Prescribing Service.[2]

Herbal medicine

In phytopharmaceutical or herbal medicine, the active ingredient may be either unknown or may require cofactors in order to achieve therapeutic goals. This leads to complications in labelling. One way manufacturers have attempted to indicate strength is to engage in standardization to a marker compound. However, standardization has not been achieved yet: different companies use different markers, or different levels of the same markers, or different methods of testing for marker compounds. For instance, St John's wort is often standardized to the hypericin which is now known not to be the "active ingredient" for antidepressant use. Other companies standardize to hyperforin or both, although there may be some 24 known possible active constituents. Many herbalists believe that the active ingredient in a plant is the plant itself.[3]

See also

References

  1. ^ Lee, D; Marks, JM. "Drug Interactions: Know the Ingredients, Consult Your Physician". Last reviewed April 14, 2009
  2. ^ Medicine Name Finder
  3. ^ 1992, American Herbalism edited by Michael Tierra Crossings Press

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