Tuscumbia is a city in Alabama, United States, a village in Miller County, Missouri, United States, or a river found in northern Mississippi and western Tennessee.

The longest river in the United States is the Mississippi River.

Alabama is east of the Mississippi River. Located in the southeastern region of the United States, it shares its eastern border with the state of Mississippi.

There are 18 states that make up the Central United States. North Dakota, South Dakota, Nebraska, Kansas, Alabama, Oklahoma, Texas and Florida are the central states that do not border the Mississippi River.

The Mississippi River is the second longest river in the United states, after the Missouri River. It forms the border of, or runs through, ten different states: Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi and Louisiana.