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The Alpha 1 Antitrypsin Deficiency means that the body does not make enough protein to protect the liver and lungs from damage. AAT is given to patients to help them produce some protein. If the patient smokes they are advised to quit.

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Although the wide majority of Alpha 1's are of Northern European decent, most of us are not of one pure race. If he is an Alpha then both of his parents would have to be carriers of the gene. A simple blood test can determine if he was an Alpha and I don't know if that was done. Alpha 1 deficiency can cause either chronic COPD or liver disease.

No one knows if Michael Jackson had Alpha-1 Antitrypsin Deficiency.

The only source for the claim is Ian Halperin, a writer who did a biography of Jackson. Halperin provided no evidence whatever for this claim, and Jackson's spokesman denied it as "a total fabrication."

Alpha-1 is considered rare in African Americans. However, the Alpha-1 Foundation recently awarded a grant to study the high rate of lung disease in African Americans, and to test them for Alpha-1 Antitrypsin Deficiency.

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The number of Americans with this deficiency is relatively small, probably no greater than 70,000

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People with this type of emphysema have a hereditary deficiency of a blood component, an enzyme inhibitor called alpha-1-antitrypsin

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