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An alphavirus is a virus of the genus Alphavius, a group IV virus which has a positive sense, single-stranded RNA genome.

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An alphavirus is a virus of the genus Alphavius, a group IV virus which has a positive sense, single-stranded RNA genome.

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It's just known as Chikungunya virus, and it belongs to genus Alphavirus.

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If you are looking for the medical terminology for yellow fever, here are some common names for it.

1. Yellow Jack

2. Black Vomit

3. American Plague

4. Vomito Negro (this means Black Vomit in spanish)

The virus that causes yellow fever is called ALPHAVIRUS (Genus) which is a RNA virus, in the Family TOGAVIRIDAE.

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Chikungunya (in the Makonde language "that which bends up") virus (CHIKV) is an insect-borne virus, of the genus Alphavirus, that is transmitted to humans by virus-carrying Aedesmosquitoes.[1] There have been recent breakouts of CHIKV associated with severe illness. CHIKV infection causes an illness with symptoms similar to dengue fever, with an acute febrilephase of the illness lasting only two to five days, followed by a prolonged arthralgic disease that affects the joints of the extremities. The pain associated with CHIKV infection of the joints persists for weeks or months, or in some cases years.[2][3]

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Replication of the HEV genome:- ü HEV replicates in the hepatocytes and is excreted in stool ü A general model of HEV replication has been proposed, based on similarities and sequence homology to other more completely characterized +RNA viruses. ü As HEV enters into a permissive cell, the viral genomic RNA is translated in the cytosol of infected cells to produce the nonstructural ORF1-encoded polyprotein (nsP). ü Because it contains the viral replicase, nsP is postulated to replicate the genomic positive strand into the negative strand replicative intermediate. ü This intermediate, in analogy with alphaviruses, is postulated to act as a template for the synthesis of additional copies of the genomic positive strand as well as a subgenomic positive strand. ü The analogy to alphavirus replication is presumed because of the presence in HEV negative-strand RNA of a sequence stretch that is similar to the junction sequence found in the RNA replicative intermediate of the Sindbis alphavirus. ü During alphavirus RNA replication, this junction sequence acts as a subgenomic promoter for transcription of the structural region mRNA. ü The proposed subgenomic positive-strand HEV RNA can then be translated into the structural protein(s) at late stages of viral replication. ü The structural (capsid) protein then probably packages the viral genome to form progeny virions. ü However, direct experimental confirmation of this replication scheme is still awaited.

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