An ampholyte is an amphoteric electrolyte.

Amphiphile is a term describing a chemical compound possessing both hydrophilic and lipophilic properties

Yes, DNA is an amphiphile

as it has hydrophobic and hydrophilic

parts. However this does not mean it is surface active!

One great strategy to tackle difficulties in membrane protein crystallization is our bicelle-protein crystallization technique. Bicelles are small bilayer disks formed in lipid/amphiphile mixtures, into which membrane proteins can be incorporated. At low temperature, bicelle-forming lipid/amphiphile mixtures are not viscous, but they tend to develop a gel-like consistency at higher temperatures. Thus, with bicelle forming lipid/amphiphile mixtures it is possible to access a variety of lipid bilayer structures simply by varying temperature.

Scott William Barton has written:

'In-plane x-ray diffraction from pure and amphiphile covered liquid surfaces'